姓名:张根林
出生年月:1981年11月
职称:教授
邮箱:zhgl_food@sina.com
研究方向:
(1)植物天然产物的生物合成
(2)酵母代谢工程和合成生物学
(3)微生物生物农药
个人简介
张根林,男,汉族,现为石河子大学化学化工学院环境与生物工程系教师,博士生导师。2015年毕业于北京理工大学,获生物化工博士学位,兵团英才,兵团中青年科技创新领军人才,石河子大学“3152”学科带头人。兼任中国生物工程学会合成生物学专业委员会委员,亚洲合成生物学联盟委员,《Frontiers in Bioengineering and Biotechnology》synthetic biology section副主编、《合成生物学》编委。
科研项目
1. 国家自然科学基金面上项目,酵母转录终止因子Pcf11的作用机制及新型转录调控工具研究,22178226,2022.1-2025.12
2. 国家自然科学基金面上项目,酿酒酵母终止子元件的设计及途径工程应用,21676167,2017.01-2020.12
3. 兵团重点领域科技攻关项目,高效微生物源生物农药的创制及产品示范,2022AB008,2022.1-2024.12
4. 兵团重点领域科技攻关项目,中药加工固废资源化利用关键技术研究与应用,2020AB026,2020.1-2022.12
5. 企业委托,农业功能微生物资源库的构建及发酵工艺,2022.07-2023.07
代表性论文:
1. Jinyu Zhao, Yuanyuan Li, Lijuan Yi, Genlin Zhang,* Bangce Ye. Yeast-based whole-cell factory for the ecofriendly synthesis of vanillylamine as a critical step toward capsaicin production. ACS Sustainable Chemistry &. Engineering, 2023, 11, 7683−7691. (SCI一区)
2. Qianyun Zhou, Hao Li, Baojin Jia, Yanyan Dang, Genlin Zhang*.One-pot synthesis of porous carbon from Chinese medicine residues driven by potassium citrate and application in supercapacitors. Journal of Analytical and Applied Pyrolysis, 2023, 170, 105894. (SCI二区)
3. Hao Li, Baojin Jia, Liwei Chen, Qianyun Zhou, Genlin Zhang,*, Yanyan Dang, Hebin Wang*. Hydrangea-like NiCo-layered double hydroxide core-shell structure growing on licorice porous carbon for high-performance supercapacitors. Diamond & Related Materials,2023, 135, 109876. (SCI二区)
4. Jiachen Sun,Wentao Sun, Genlin Zhang*, BoLv*, ChunLi*. High efficient production of plant flavonoids by microbial cell factories: Challenges and opportunities. Metabolic Engineering, 2022,70, 143-154. (SCI一区)
5. Shaobo Bo, Xiaoxia Ni, Jintang Guo, Zhengyang Liu, Xiaoya Wang, Yue Sheng, Genlin Zhang,* Jinfeng Yang*.Carotenoid biosynthesis: genome-wide profiling, pathway identification in Rhodotorula glutinis X-20, and high-level production. Frontiers in Nutrition, 2022, 9, 918240. (SCI二区)
6. Di Qiu, Minghai Wang, Chao Zhou, Jinyu Zhao, Genlin Zhang*. De novo biosynthesis of vanillin in engineered Saccharomyces cerevisiae. Chemical Engineering Science, 2022, 263, 118049. (SCI二区)
7. Hao Li, Liwei Chen, Qianyun Zhou, Di Qiu, Genlin Zhang,* Yanyan Dang. NiCo2O4 used as a loading material to improve the capacitive performance of nitrogen-doped carbon aerogel. Journal of Materials Science, 2022,57, 12497–12510. (SCI二区)
8. Xiaoya Wang, Genlin Zhang,* Yanyan Dang*. Enhanced Extraction of Flavonoids from Licorice Residues by Solid-State Mixed Fermentation.Waste and Biomass Valorization, 2022, 13, 4481-4493. (SCI三区)
9. Aijun Qiu, Yunyun Wang, Genlin Zhang*, Hebin Wang*. Natural Polysaccharide-Based Nanodrug Delivery Systems for Treatment of Diabetes. Polymers, 2022,14(15), 3217 (SCI二区)
10. Xia Li, Zhaoxia Wang, Genlin Zhang*, Lijuan Yi*. Improving lycopene production in Saccharomyces cerevisiae through optimizing pathway and chassis metabolism. Chemical Engineering Science, 2019,193,364-369. (SCI二区)
11. Ming Zhu, Caixia Wang, Wentao Sun, Anqi Zhou, Ying Wang, Genlin Zhang, Xiaohong Zhou, Yixin Huo, Chun Li*. Boosting 11-oxo-β-amyrin and glycyrrhetinic acid synthesis in Saccharomyces cerevisiae via pairing novel oxidation and reduction system from legume plants. Metabolic Engineering, 2018, 45: 43–50. (SCI一区)
12. LinnaWei, Zhaoxia Wang, Genlin Zhang* and Bangce Ye. Characterization of terminatorsin Saccharomyces cerevisiae and exploration factors affecting their strength. ChemBioChem,2017, 18:1-7. (SCI二区)
13. Genlin Zhang,Qian Cao, Jingzhu Liu, Baiyang Liu, Jun Li, Chun Li*. Refactoring β-Amyrin Synthesis in Saccharomyces cerevisiae. AIChE Journal, 2015,61(10):3172-3179.(SCI二区)
发明专利:
1.张根林,刘政洋,倪晓霞,张燕. 一种具有启动、终止双功能调控元件的构建方法、双功能元件库和应用, 中国发明专利,ZL202110211960.2
2.张根林,李霞,赵金雨. 一种酿酒酵母菌、其构建方法及其在发酵制备番茄红素中的应用,中国发明专利,ZL201810311320.7
3.张根林,刘政洋,倪晓霞,张燕. Construction method of regulatory element having dual functions of promotion and termination, and bifunctional element library, PCT/CN2021/077808
4.张根林,陈利威,周倩云,党艳艳. Licorice root residue-based hierarchical porous carbon, preparation method and application thereof, 2020101074
5.党艳艳,李张莲,张根林. Extraction method for polysaccharide in plants,Lu501444
6.党艳艳,付晓茜,张根林,邓辉,马娜. 一种提取分离万寿菊中叶黄素的方法, 中国发明专利,ZL201810696234.2
获奖情况:
1.国家教育部技术发明奖,二等奖,耐盐防病促生菌剂的研制及产业化
2.兵团科学技术进步奖,二等奖,肥料农药高效利用科学基础及关键技术
3.2014国际遗传机器竞赛金奖
4.2015年国际遗传机器竞赛金奖,最佳应用提名奖
5.2016年中国石油和化学工业联合会优秀出版物奖——教材奖一等奖(生物工程与技术导论)
6.石河子大学优秀研究生指导教师