基本情况:
李永生,男,1972年12月出生。E-mail--ysli@ecust.edu.cn;联系电话-13661471735;招生专业/人员:材料科学与工程(材料、化学、生物/药学/医学、新能源)硕士、博士研究生及博士后。
教育/工作经历:
2020.11-至今 石河子大学 教授
2009.09 - 2020.10 华东理工大学 教授
2006.01 - 2009.08 华东理工大学 副教授
2005.01 - 2005.12 上海交通大学 副教授
2003.03 - 2004.12 法国国家科研中心里昂催化所 博士后(合作导师:Jean-Alain Dalmon研究员)
2001.07 - 2003.02 中国科学院上海硅酸盐研究所 博士后(合作导师:严东生院士、施剑林院士)
1996.09 - 2001.06 大连理工大学 博士(导师:郭树才教授、王金渠教授)
1990.09 - 1994.06 郑州大学 学士
研究方向:
主要从事杂化生物材料、多孔材料及能源催化应用等研究。包括:
1. 杂化生物材料及其疾病精准诊断和治疗性能
2. 新型介孔材料及其药物载体和肿瘤治疗治疗性能
3. 多级结构材料及其催化和二次电池性能
主要成果:
围绕有机-无机杂化材料的制备及其在生物、催化能源方面的应用开展了系统的研究工作,迄今发表高水平研究论文200余篇,其中,以第一/通讯作者先后在Chem. Soc. Rev.,Nat.Commun., Adv. Mater.,J. Am. Chem. Soc.,Adv. Funct./Energy Mater., Biomaterials等国际著名期刊上发表论文120余篇,10余篇入选ESI高被引论文。全部论文SCI他引12500余次,h指数 59。主持国家重点研发计划、国家自然科学基金、上海市科委基础重点等项目1,入选国家高层次人才、国家百千万人才工程及“有突出贡献中青年专家”、教育部新世纪优秀人才、上海市“优秀学科带头人”、上海领军人才和上海市“曙光学者”等,曾获上海市育才奖和上海市自然科学一等奖(排名第二)等。
主要社会兼职:
1. 中国生物材料学会 理事
2. 中国生物材料学会纳米生物材料分会 副主任委员兼总秘书长
3. 无机材料学报 编委
4. 超细材料制备与应用教育部重点实验室 副主任
代表性论文(第一或通讯作者):
1.Zhiqing Liu, Wei Li*, Wenbo Sheng, Shiyu Liu, Rui Li, Qian Li, Danya Li, Shui Yu, Meng Li, Yongsheng Li*, and Xin Jia*, Tunable Hierarchically Structured Meso-Macroporous Carbon Spheres from a Solvent-Mediated Polymerization-Induced Self-Assembly, J. Am. Chem. Soc., 2023, doi.org/10.1021/jacs.2c12977.
2. Limei Qin, Jie Gan, Dechao Niu, Yueqiang Cao, Xuezhi Duan, Xing Qin, Hao Zhang, Zheng Jiang, Yongjun Jiang, Sheng Dai, Yongsheng Li* and Jianlin Shi, Interfacial-confined coordination to single-atom nanotherapeutics, Nat. Commun., 2022, 13, 91.
3. Xianglong Li, Cong Jiang, Qinghua Wang, Shaobo Yang, Yuanyuan Cao, Ji-Na Hao*,Dechao Niu, Yan Chen, Bo Han, Xin Jia, Peng Zhang*, and Yongsheng Li*, A “Valve-Closing” Starvation Strategy for Amplification of Tumor-Specific Chemotherapy, Adv. Sci., 2022, 9, 2104671.
4. Xing Qin, Chu Wu, Dechao Niu*, Limei Qin, Xia Wang*, Qigang Wang*, Yongsheng Li*, Peroxisome Inspired Hybrid Enzyme Nanogels for Chemodynamic and Photodynamic Therapy, Nat. Commun., 2021, 12, 5243.
5. Xianjing Jia, Yunfeng Yan, A. Basak Kayitmazer, Yongsheng Li*, and Yisheng Xu*, Scalable Yielding of Highly Stable Polyelectrolyte-Coated Copper Sulfide Nanoparticles by Flash Nanoprecipitation for Photothermal-Chemotherapeutics, Adv. Funct. Mater., 2021, 2100452.
6. Shaobo Yang, Dechao Niu*, Nan Li, Jinlou G, Xu Dai, Tiangang Yang, Xiang Gao, Yongsheng Li*, Jianlin Shi, Block Copolymer Nanoparticle Replicating Strategy Towards Hierarchically Mesoporous Structured Silica with Predictable Architectures, Science Bulletin, 2021, 66, 197-199.
7. Guangyu Jiang, Kaiyuan Li, Feng Yu, Xianglong Li, Jiayi Mao, Weiwei Jiang, Fugen Sun*, Bin Dai*, Yongsheng Li*, Robust Artificial Solid-Electrolyte Interfaces with Biomimetic Ionic Channels for Dendrite-Free Li Metal Anodes, Adv. Energy Mater., 2021, 11, 2003496.
8. Ji-Na Hao, Dechao Niu, Jinlou Gu, Shaoliang Lin*, Yongsheng Li*, Jianlin Shi, Structure Engineering of a Lanthanide-Based Metal–Organic Framework for the Regulation of Dynamic Ranges and Sensitivities for Pheochromocytoma Diagnosis, Adv. Mater., 2020, 32, 2000791.
9. Ji-Na Hao, Yongsheng Li*, Concurrent Modulation of Competitive Mechanisms to Design Stimuli-Responsive Ln-MOFs: A Light-Operated Dual-Mode Assay for Oxidative DNA Damage, Adv. Funct. Mater., 2019, 29, 1903058.
10. Xiaobo Jia, Jianping He, Luying Shen, Jianzhuang Chen, Zhenyang Wei, Xing Qin, Dechao Niu*, Yongsheng Li*, Jianlin Shi, Gradient Redox-Responsive and Two-Stage Rocket-Mimetic Drug Delivery System for Improved Tumor Accumulation and Safe Chemotherapy, Nano Lett., 2019, 19, 8690-8700.
11. Xiaobo Jia, Yihua Zhang, Yu Zou, Yao Wang, Dechao Niu, Qianjun He, Zhangjian Huang*, Weihong Zhu, He Tian, Jianlin Shi, and Yongsheng Li*, Dual intratumoral redox/enzyme-responsive NO-releasing nanomedicine for the specific, high-efficacy, and low-toxic cancer therapy, Adv. Mater., 2018, 30, 1704490. (Cover paper)
12. Dechao Niu, Yongsheng Li* and Jianlin Shi*, Silica/organosilica cross-linked block copolymer micelles: a versatile theranostic platform, Chem. Soc. Rev., 2017, 46, 569.
13. Nan Li, Dechao Niu, Yu Jiang, Chuanpeng Xu, Shan Pan, Jianping He, Jianzhuang Chen, Linlin Zhang, Yongsheng Li*, Morphology evolution and spatially selective functionalization of hierarchically porous silica nanospheres for improved multidrug delivery, Chem. Mater., 2017, 29, 10377.
14. Yongsheng Li*, Andong Shao, Yao Wang, Ju Mei, Dechao Niu, Jinlou Gu, Ping Shi, Weihong Zhu*, He Tian, and Jianlin Shi, Morphology-tailoring of a red AIEgen from microsized rods to nanospheres for tumor-targeted bioimaging, Adv. Mater., 2016, 28, 3187 (Cover paper).
15. Fugen Sun, Hongye Cheng, Jianzhuang Chen, Nan Zheng, Yongsheng Li* and Jianlin Shi*, Heteroatomic SenS8−n molecules confined in nitrogen-doped mesoporous carbons as reversible cathode materials for high-performance lithium batteries, ACS Nano, 2016, 10, 8289.
16. Pei-Pei Yang, Yun-Gang Zhai, Guo-Bin Qi, Yao-Xin Lin, Qiang Luo, Yang Yang, An-Ping Xu, Chao Yang, Yongsheng Li*, Lei Wang*, and Hao Wang*, NIR light propulsive Janus-like nanohybrids for enhanced photothermal tumor therapy, Small, 2016, 12, 5423.
17. Yongping Gao, Yongsheng Li*, Yao Wang, Yi Chen, Jinlou Gu, Wenru Zhao, Jian Ding, and Jianlin Shi*, Controlled synthesis of multilayered gold nanoshells for enhanced photothermal therapy and SERS detection, Small, 2015, 11, 77.
18. Yongping Gao, Yongsheng Li*, Jianzhuang Chen, Shaojia Zhu, Xiaohang Liu, Liangping Zhou, Ping Shi, Dechao Niu, Jinlou Gu, and Jianlin Shi*, Multifunctional gold nanostar-based nanocomposite: Synthesis and application for noninvasive MR-SERS imaging-guided photothermal ablation, Biomaterials, 2015, 60, 31.
19. Dechao Niu, Zuojin Liu, Yongsheng Li,* Xiaofeng Luo, Junyong Zhang, Jianping Gong,*and Jianlin Shi*Monodispersed and ordered large-pore mesoporous silica nanospheres with tunable pore structure for magnetic functionalization and gene delivery, Adv. Mater., 2014, 26, 4947. (Cover paper)
20. Yongsheng Li* and Jianlin Shi*, Hollow-structured mesoporous materials: chemical synthesis, functionalization and Applications, Adv. Mater., 2014, 26, 3176.
21. Dechao Niu, Xia Wang, Yongsheng Li*, Yuanyi Zheng, Faqi Li, Hangrong Chen, Jinlou Gu, Wenru Zhao, and Jianlin Shi*, Facile synthesis of magnetite/perfluorocarbon co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging- guided high-intensity focused ultrasound ablation, Adv. Mater., 2013, 25, 2686.
22. Shu Chang, Xumeng Wu, Yongsheng Li*, Dechao Niu, Yongping Gao, Zhi Ma, Jinlou Gu, Wenru Zhao, Weihong Zhu*, He Tian, Jianlin Shi*, A pH-responsive hybrid fluorescent nanoprober for real time cell labeling and endocytosis tracking, Biomaterials, 2013, 34, 10182.
23. Wenjie Dong, Yongsheng Li*, Dechao Niu, Zhi Ma,Jinlou Gu, Yi Chen, Wenru Zhao, Xiaohang Liu, Changsheng Liu, and Jianlin Shi*, Facile synthesis of monodisperse superparamagetic Fe3O4 core@hybrid@Au shell nanocomposite for bimodal imaging and photothermal therapy, Adv. Mater., 2011, 23, 5392.
24. Dechao Niu, Yongsheng Li*, Zhi Ma, Hua Diao, Jinlou Gu, Hangrong Chen, Wenru Zhao, Meiling Ruan, Yonglian Zhang, and Jianlin Shi*, Preparation of uniform, water-aoluble, and multifunctional nanocomposites with tunable sizes, Adv. Funct. Mater., 2010, 20, 773.
25. Dechao Niu, Zhi Ma, Yongsheng Li*, and Jianlin Shi*, Synthesis of core-shell structured dual-mesoporous silica spheres with tunable pore size and controllable shell thickness, J. Am. Chem. Soc., 2010, 132, 15144.
出版著作:
1. Yongping Gao, Yongsheng Li, Gold nanostructures for cancer imaging and therapy” in Advances in nanotheranostics I: Design and fabrication of theranosic nanoparticles, Springer Berlin Heidelberg: Berlin, Heidelberf, 2016.
2. 张兴棣,李永生,主编:刘昌胜,硬组织修复材料与技术:介孔生物玻璃与骨修复(第4章),科学出版社,2014。