工学博士，教授、博士生导师。作为课题负责人主持了973、863、国家自然科学基金课题、以及中石油等工业应用课题数十项。上海市浦江人才计划学者。现任AppliedBiochemistryandBiotechnology和Bioprocess and Biosystems Engineering期刊副主编、ACSSustainableChemistryandEngineering编委、Springer和Elsevier学术期刊客座编辑。研究领域聚焦于生物能源和生物炼制方向。提出了木质纤维素干法生物炼制技术，在液体燃料和生物基化学品生产上显示了巨大的技术优势和环境友好性，奠定了以木质纤维素替代粮食和石油资源的可持续生物与化学工业的技术基础；面向生物能源和生物聚合物生产的超级生物炼制微生物的发现、进化和代谢工程改造，成倍提高了生物转化效率，达到了迄今国内外最高水平的生物炼制转化、能耗和排放指标；独特的生物脱毒菌株和代谢机制的发现，极大提高了生物炼制过程效率和环境质量，实现了抑制物脱毒关键瓶颈的突破；提出了基于严格热力学和流变学基础上的生物炼制流程模拟和计算流体力学模型，实施了多项面向产业化规模的工艺包设计和工业应用。
联系方式
通讯地址：上海市梅陇路130号华东理工大学283信箱（200237）
实验室位置：华东理工大学实验十八楼1303室
实验室网页：http://sklbe.ecust.edu.cn/biomasslab
电话/传真：021-64251799
Email：jbao@ecust.edu.cn
学历
1997-2001工学博士，日本国立山口大学物质工学专业
1995-1997工学硕士，浙江大学化学工程专业
1980-1984工学学士，南京理工大学化学工程专业
研究经历
2006-现在华东理工大学生物工程学院教授、博士生导师
2001-2006美国加州大学戴维斯分校博士后研究员
1984-1995中石化齐鲁石化研究院工程师、课题组长
学术兼职
1.AppliedBiochemistryandBiotechnology(Springer)副主编(AssociateEditor)
2.Bioprocess and Biosystems Engineering (Springer) 副主编 (Associate Editor)
3.ACS Sustainable Chemistry and Engineering (ACS) 编委 (Editorial Board Member)
学术著作
1.Bioreactor Engineering Research and Industrial Applications II, Advances in Biochemical Engineering/Biotechnology, Volume 152, 2016. Editors: Jie Bao, Qin Ye, Jian-Jiang Zhong. ISBN: 978-3-662-48346-6 (Print), 978-3-662-48347-3 (eBook). Springer, Berlin, Heidelberg, Germany, 2016.
2.Bioreactor Engineering Research and Industrial Applications I, Advances in Biochemical Engineering /Biotechnology, Volume 155, 2016. Editor: Editors: Qin Ye, Jie Bao, Jian-Jiang Zhong. ISBN: 978-3-662-49159-1 (Print), 978-3-662-49161-4 (eBook). Springer, Berlin, Heidelberg, Germany, 2016.
3.生物炼制产品与技术，鲍杰，高秋强，张建，曹学君，邓红波。上海科学技术出版社，2013. ISBN 978-7-5478-1568-7.
4.现代生物能源技术（应用生物技术大系丛书），鲍杰，科学出版社，2009. ISBN
本年度(2018-2019)代表性论文(*为通讯作者)
1.Zhao Yan1, Xiaochuang Gao1, Qiuqiang Gao, Jie Bao*. Identification, tolerance mechanism and metabolic modification of biorefinery fermentation strains to lignin derived inhibitor p-benzoquinone.Applied and Environmental Microbiology2019, DOI: 10.1128/AEM.01443-19.
2.Pingping Zhou1, Ruimiao Yao1, Hongsen Zhang, Jie Bao*. Unique glucose oxidation catalysis of Gluconobacteroxydans constitutes an efficient cellulosic gluconic acid fermentation free of inhibitory compounds disturbance. Biotechnology and Bioengineering 2019, 116:2191-2199.
3.Xia Yi1, Qiuqiang Gao1, Lei Zhang1, Xia Wang, Yanqing He, Fengxian Hu, Jian Zhang, Gen Zou, Shihui Yang, Zhihua Zhou*, Jie Bao*. Heterozygous diploid structure of Amorphotheca resinae ZN1 contributes efficient biodetoxification on solid pretreated corn stover. Biotechnology for Biofuels 2019, 12:126.
4.Jingbai Wen, Jie Bao*. Engineering Corynebacterium glutamicum triggers glutamic acid accumulation in biotin rich corn stover hydrolysate. Biotechnology for Biofuels 2019, 12:86.
5.Ci Jin1, Weiliang Hou1, Ruimiao Yao1, Pingping Zhou, Hongsen Zhang, Jie Bao*. Adaptive evolution of Gluconobacteroxydans accelerates the conversion rate of non-glucose sugars derived from lignocellulose biomass. Bioresource Technology 2019, 289:121623.
6.Xushen Han1, Li Li1, Jie Bao*. Microbial extraction of biotin from lignocellulose biomass and its application on glutamic acid production. Bioresource Technology 2019, 288:121523.
7.Zeyu Chen1, Gang Liu1, Jian Zhang*, Jie Bao. A preliminary study on L-lysine fermentation from lignocellulose feedstock and techno-economic evaluation. Bioresource Technology 2019, 271:196-201.
8.Gang Liu, Jie Bao*. Constructing super large scale cellulosic ethanol plant by decentralizing dry acid pretreatment technology into biomass collection depots. Bioresource Technology 2019, 275:338-344.
9.Xushen Han1, Li Li1, Chengxiang Wei, Jian Zhang, Jie Bao*. Rich vitamins B in lignocellulose biomass facilitates L-lactic acid fermentation. Journal of Agricultural and Food Chemistry 2019, 67:7082-7086.
10.Pingping Zhou1, Imrana Khushk1, Qiuqiang Gao, Jie Bao*. Tolerance and transcriptional analysis of Corynebacterium glutamicum on biotransformation of toxic furaldehyde and benzaldehyde inhibitory compounds. Journal of Industrial Microbiology & Biotechnology 2019, 46:951-963.
11.Xia Yi, Qiuqiang Gao, Jie Bao*. Expressing an oxidative dehydrogenase gene in ethanologenic strain Zymomonas mobilis promotes the cellulosic ethanol fermentability. Journal of Biotechnology2019, 303:1-7.
12.Weiliang Hou1, Jialun Kan1, Jie Bao*. Rheology evolution of high solids content and highly viscous lignocellulose system in biorefinery fermentations for production of biofuels and biochemicals. Fuel 2019, 253:1565-1569.
13.Weitao Dong, Xushen Han, Gang Liu*, Jie Bao*. Improving cellulosic ethanol fermentation efficiency by converting endogenous water soluble carbohydrates into citric acid before pretreatment. Bioprocess and Biosystems Engineering. Bioprocess and Biosystems Engineering 2019, 42:1099-1103.
14.MesfinGeberekidan, Jian Zhang*, Z. Lewis Liu*, Jie Bao. Improved cellulosic ethanol production from corn stover with a low cellulase input using a β-glucosidase producing yeast following a dry biorefining process. Bioprocess and Biosystems Engineering 2019, 42:297-304.
15.Gang Liu1, Qiang Zhang1, Hongxing Li, Abdul SattarQurishi, Jian Zhang, Xiaoming Bao*, Jie Bao*. Dry biorefining maximizes the potentials of simultaneous saccharification and co-fermentation for cellulosic ethanol production.Biotechnology and Bioengineering2018, 115, 60-69.
16.Jingbai Wen, Yanqiu Xiao, Ting Liu, Qiuqiang Gao, Jie Bao*. Rich biotin content in lignocellulose biomass plays the key role in determining cellulosic glutamic acid accumulation by Corynebacterium glutamicum.Biotechnology for Biofuels2018, 11, 132.
17.HanqiGu, Ruixin An, Jie Bao*. Pretreatment refining leads to constant particle size distribution of lignocellulose biomass in enzymatic hydrolysis.Chemical Engineering Journal2018, 352:198-205.
18.Xushen Han, Jie Bao*.General method on correcting the fluctuation of acid based pretreatment efficiency of lignocellulose for highly efficient bioconversion.ACS Sustainable Chemistry & Engineering2018,6(3):4212-4219.
19.WeiliangHou, Maofen Zhang, Jie Bao*. Cascade hydrolysis and fermentation of corn stover for production of high titer gluconic and xylonic acids.Bioresource Technology2018, 264:395-399.
20.WeiliangHou, Jie Bao*. Simultaneous saccharification and aerobic fermentation of high titer cellulosic citric acid by filamentous fungusAspergillus niger.Bioresource Technology2018,253,72-78.
21.ZhongyangQiu, Qiuqiang Gao, Jie Bao*.EngineeringPediococcus acidilacticiwith xylose assimilation pathway for high titer cellulosic L-lactic acid fermentation.Bioresource Technology 2018, 249, 9-15.
22.XushenHan,FengHong,GangLiu,Jie Bao*.AnapproachofutilizingwatersolublecarbohydratesinlignocellulosefeedstockforpromotionofcellulosicL-lacticacidproduction.JournalofAgriculturalandFoodChemistry2018,66:10225-10232.
23.ChengxiangWei#,GangLiu#,JianZhang*,Jie Bao*.Elevatingfermentationyieldofcellulosiclacticacidincalciumlactateformfromcornstoverfeedstock.IndustrialCropsandProducts2018,126:415-420.
24.XiaWang1,ImranaKhushk1,YanqiuXiao,QiuqiangGao*,Jie Bao.ToleranceimprovementofCorynebacteriumglutamicumonlignocellulosederivedinhibitorsbyadaptiveevolution.AppliedMicrobiologyandBiotechnology2018,102:377-388.
25.MingshanHu,JuanWang,QiuqiangGao*,Jie Bao*.ConvertingligninderivedphenolicaldehydesintomicrobiallipidbyTrichosporoncutaneum.JournalofBiotechnology2018,281,81-86.
26.XiaochuangGao,QiuqiangGao,Jie Bao*.ImprovingcellulosicethanolfermentabilityofZymomonasmobilisbyoverexpressionofsodiumiontolerancegeneZMO0119.JournalofBiotechnology2018,282,32-37.
27.XiaochuangGao,QiuqiangGao*,Jie Bao*.ToleranceresponseandmetabolismofaceticacidbybiodetoxificationfungusAmorphothecaresinaeZN1.JournalofBiotechnology2018,275,31-39.
近期代表性论文(*为通讯作者)
1.JianZhang*,ChengLei,GangLiu,YanwenBao,VenkateshBalan*,JieBao*.In-situvacuumdistillationofethanolhelpstorecyclecellulaseandyeastduringSSFofdelignifiedcorncobresidues.ACSSustainableChemistry&Engineering2017,5,11676-11685.
2.WeiliangHou,LangLi,JieBao*.Oxygentransferinhighsolidsloadingandhighlyviscouslignocellulosehydrolysates.ACSSustainableChemistry&Engineering2017,5,11395-11402.
3.AbdulSattarQureshi,JianZhang*,LeonardodaCostaSousa*,JieBao*.AnantibacterialpeptidesecretedbyPediococcusacidilacticienablesefficientcellulosicopenL-lacticacidfermentation.ACSSustainableChemistry&Engineering2017,5,9254-9262.
4.YiJiang1,KuimeiLiu1,HongsenZhang,YingliWang,QuanquanYuan,NingSu,JieBao, XuFang*.GluconicacidproductionfrompotatowastebyGluconobacteroxidansusingsequentialhydrolysisandfermentation.ACSSustainableChemistry&Engineering2017,5,6116-6123.
5.RuimiaoYao1,WeiliangHou1,JieBao*.Completeoxidativeconversionoflignocellulosederivednon-glucosesugarstosugaracidsbyGluconobacteroxydans.BioresourceTechnology2017,244:1188-1192.
6.GangLiu,JieBao*.Maximizingcellulosicethanolpotentialsbyminimizingwastewatergenerationandenergyconsumption:Competingwithcornethanol.BioresourceTechnology2017,245:18-26.
7.GangLiu,JieBao*.Evaluationofelectricitygenerationfromligninresidueandbiogasincellulosicethanolproduction.BioresourceTechnology2017,243:1232-1236.
8.ZhongyangQiu,QiuqiangGao,JieBao*.Constructingxylose-assimilatingpathwaysinPediococcusacidilacticiforhightiterD-lacticacidfermentationfromcornstoverfeedstock.BioresourceTechnology2017,245,1369-1376.
9.Ping-PingZhou,JiaoMeng,JieBao*.Fermentativeproductionofhightitercitricacidfromcornstoverfeedstockafterdrydiluteacidpretreatmentandbiodetoxification.BioresourceTechnology2017,224:563-572.
10.HongsenZhang1,XushenHan1,ChengxiangWei1,JieBao*.OxidativeproductionofxylonicacidusingxyloseindistillationstillageofcellulosicethanolfermentationbrothbyGluconobacteroxydans.BioresourceTechnology2017,224:573-580.
11.ShuaiShao,JianZhang*,WeiliangHou,AbdulSattarQureshi,JieBao.Lowerpressureheatingsteamispracticalforthedistributeddrydilutesulfuricacidpretreatment.BioresourceTechnology2017,238:744-748.
12.XiaWang,QiuqiangGao,JieBao*.EnhancementoffuranaldehydesconversioninZymomonasmobilisbyelevatingdehydrogenaseactivityandcofactorregeneration.BiotechnologyforBiofuels2017,10:24.
13.DongTian,JinguangHu*,JieBao,RichardP.Chandra,JackN.Saddler,CanhuiLu*.Ligninvalorization:ligninnanoparticlesashigh-valuebio-additiveformultifunctionalnanocomposites.BiotechnologyforBiofuels2017,10:192.
14.HongsenZhang1,GangLiu1,JianZhang,JieBao*.FermentativeproductionofhightitergluconicandxylonicacidsfromcornstoverfeedstockbyGluconobacteroxydansandtechno-economicanalysis.BioresourceTechnology2016,219:123-131.
15.HongsenZhang,JianZhang,JieBao*.HightitergluconicacidfermentationbyAspergillusnigerfromdrydiluteacidpretreatedcornstoverwithoutdetoxification.BioresourceTechnology2016,203:211-219.
16.JuanWang,QiuqiangGao,HuizhanZhang,JieBao*.InhibitordegradationandlipidaccumulationpotentialsofoleaginousyeastTrichosporoncutaneumusinglignocellulosefeedstock.BioresourceTechnology2016,218:892-901.
17.JianZhang1,ShuaiShao1,JieBao*.Longtermstorageofdiluteacidpretreatedcornstoverfeedstockandethanolfermentabilityevaluation.BioresourceTechnology2016,201:355-359.
18.YanqingHe,JianZhang,JieBao*.Accelerationofbiodetoxificationondiluteacidpretreatedlignocellulosefeedstockbyaerationandtheconsequentethanolfermentationevaluation.BiotechnologyforBiofuels2016,9:19.
19.HanqiGu,JianZhang,JieBao*.HightoleranceandphysiologicalmechanismofZymomonasmobilistophenolicinhibitorsinethanolfermentationofcorncobresidue.BiotechnologyandBioengineering,2015,112:1770-1782.
20.XiaYi,HanqiGu,QiuqiangGao,Z.LewisLiu*,JieBao*.TranscriptomeanalysisofZymomonasmobilisZM4revealsmechanismsoftoleranceanddetoxificationofphenolicaldehydeinhibitorsfromlignocellulosepretreatment.BiotechnologyforBiofuels,2015,8:153.
21.XiaWang,QiuqiangGao,JieBao*.TranscriptionalanalysisofAmorphothecaresinaeZN1onbiologicaldegradationoffurfuraland5-hydroxymethylfurfuralderivedfromlignocellulosepretreatment.BiotechnologyforBiofuels,2015,8:136.
22.GangLiu1,JiaoeSun1,JianZhang1,YiTu,JieBao*.HightiterL-lacticacidproductionfromcornstoverwithminimumwastewatergenerationandtechno-economicevaluationbasedonAspenplusmodeling.BioresourceTechnology,2015,198:803-810.
23.KeLiu,JianZhang,JieBao*.Twostagehydrolysisofcornstoverathighsolidscontentformixingpowersavingandscale-upapplications.BioresourceTechnology,2015,196:716-720.
24.AbdulSattarQureshi,JianZhang,JieBao*.HighethanolfermentationperformanceofthedrydiluteacidpretreatedcornstoverbyanevolutionarilyadaptedSaccharomycescerevisiaestrain.BioresourceTechnology,2015,189:399-404.
25.YanqingHe,ZhenhongFang,JianZhang,XinliangLi,JieBao*.De-ashingtreatmentofcornstoverimprovestheefficienciesofenzymatichydrolysisandconsequentethanolfermentation.BioresourceTechnology2014,169:552-558.
26.ChengLei,JianZhang,LinXiao,JieBao*.Analternativefeedstockofcornmealforindustrialfuelethanolproduction:Delignifiedcorncobresidue.BioresourceTechnology2014,167:555-559.
27.YanqingHe,JianZhang,JieBao*.Drydiluteacidpretreatmentbyco-currentlyfeedingofcornstoverfeedstockanddiluteacidsolutionwithoutimpregnation.BioresourceTechnology2014,158:360-364.
28.HongRan,JianZhang,QiuqiangGao,ZhanglinLin,JieBao*.Analysisofbiodegradationperformanceoffurfuraland5-hydroxymethylfurfuralbyAmorphothecaresinaeZN1.BiotechnologyforBiofuels2014,7:51.
29.ShuhongGao,ChunYou,ScottRenneckar,JieBao,Yi-HengPercivalZhang*.Newinsightsintoenzymatichydrolysisofheterogeneouscellulosebyusingcarbohydratebindingmodule3containingGFPandcarbohydrate-bindingmodule17containingCFP.BiotechnologyforBiofuels2014,7:24.
30.YanqingHe,LongpingZhang,JianZhang*,JieBao*.Helicallyagitatedmixingindrydiluteacidpretreatmentenhancesthebioconversionofcornstoverintoethanol.BiotechnologyforBiofuels2014,7:1.
31.HanqiGu,JianZhang,JieBao*.InhibitoranalysisandadaptiveevolutionofSaccharomycescerevisiaeforsimultaneoussaccharificationandethanolfermentationfromindustrialwastecorncobresidues.BioresourceTechnology,2014,157:6-13.
32.QiuqiangGao,ZhenyangCui,JianZhang,JieBao*.LipidfermentationofcorncobresidueshydrolysatebyoleaginousyeastTrichosporoncutaneum.BioresourceTechnology2014,152:552-556.
33.LihaoGuo,JianZhang,FengxianHu,DeweyDYRyu,JieBao*.ConsolidatedbioprocessingofhighlyconcentratedJerusalemartichoketubersforsimultaneoussaccharificationandethanolfermentation.BiotechnologyandBioengineering2013,110:2606-2615.
34.HongweiDong,LiqiangFan,ZichenLu,JianjiangZhong,DeweyD.Y.Ryu,JieBao*.ImprovementofethanolproductivityandenergyefficiencybydegradationofinhibitorsusingrecombinantZymomonasmobilis(pHW20a-fdh).BiotechnologyandBioengineering2013,110:2395-2404.
35.ThaiHaDao,JianZhang,JieBao*.Characterizationofinulinhydrolyzingenzyme(s)incommercialglucoamylasesanditsapplicationinlacticacidproductionfromJerusalemartichoketubers(Jat).BioresourceTechnology2013,148:157-162.
36.JianZhang,ZhenhongFang,HongboDeng,XiaoxiZhang,JieBao*.Costanalysisofcassavacelluloseutilizationscenariosforethanolproductiononflowsheetsimulationplatform.BioresourceTechnology2013,134:298-306.
37.KaiZhao,QinganQiao,DeqiangChu,HanqiGu,ThaiHaDao,JianZhang,JieBao*.SimultaneoussaccharificationandhightiterlacticacidfermentationofcornstoverusinganewlyisolatedlacticacidbacteriumPediococcusacidilacticiDQ2.BioresourceTechnology2013,135:481-489.
38.WeiLiu,YumeiWang,ZhanchunYu,JieBao*.SimultaneoussaccharificationandmicrobiallipidfermentationofcornstoverbyoleaginousyeastTrichosporoncutaneum.BioresourceTechnology2012,118:13-14.
39.JianZhang,JieBao*.Amodifiedmethodforcalculatingpracticalethanolyieldathighlignocellulosicsolidscontentandhighethanoltiter.BioresourceTechnology2012,116:74-79.
40.XiaoHuang,YumeiWang,WeiLiu,JieBao*..BiologicalremovalofinhibitorsleadstotheimprovedlipidproductioninthelipidfermentationofcornstoverhydrolysatebyTrichosporoncutaneum.BioresourceTechnology2011,102:9705-9709.
41.JianZhang,XiushengWang,DeqiangChu,YanqingHe,JieBao*.Drypretreatmentoflignocellulosewithextremelylowsteamandwaterusageforbioethanolproduction.BioresourceTechnology2011,102:4480-4488.
42.HongweiDong,JieBao*,DeweyD.Y.Ryu*,JianjiangZhong*.DesignandconstructionofimprovednewvectorsforZymomonasmobilisrecombinants.BiotechnologyandBioengineering2011,108:1616-1627.
43.HongweiDong,JieBao*.Biofuelviabiodetoxification(NewsandViews).NatureChemicalBiology2010,6:316-318.
44.JianZhang,DeqiangChu,JuanHuang,ZhanchunYu,GanceDai,JieBao*.Simultaneoussaccharificationandethanolfermentationathighcornstoversolidsloadinginahelicalstirringbioreactor.BiotechnologyandBioengineering2010,105:718-728.
45.JianZhang,ZhinanZhu,XiaofengWang,NanWang,WeiWang,JieBao*.BiodetoxificationoftoxinsgeneratedfromlignocellulosepretreatmentusinganewlyisolatedfungusAmorphothecaresinaeZN1andtheconsequentethanolfermentation.BiotechnologyforBiofuels2010,3:26.
46.JieBao,DeweyD.Y.Ryu.TotalbiosynthesisofdeoxynucleosidetriphosphatesusingdeoxynucleosidemonophosphatekinasesforPCRapplication.BiotechnologyandBioengineering2007,98:1-11.
47.JieBao,DeweyD.Y.Ryu.Cloningofdeoxynucleosidemonophosphatekinasegenesandbiosynthesisofdeoxynucleosidediphosphates.BiotechnologyandBioengineering2006,93:572-580.
48.JieBao,BuliangGao,XiaofengWu,MakotoYoshimoto,KatsumiNakao.Simulationofindustrialcatalytic-distillationprocessforproductionofmethyltert-butyletherbydevelopinguser’smodelonAspenplusplatform.ChemicalEngineeringJournal2002,90:253-266.
49.JieBao,KenichiKoumatsu,KeijiFurumoto,MakotoYoshimoto,KimitoshiFukunaga,KatsumiNakao.Optimaloperationofanintegratedbioreaction-crystallizationprocessforcontinuousproductionofcalciumgluconateusingexternalloopairliftcolumns.ChemicalEngineeringScience2001,56:6165-6170.
50.JieBao,KeijiFurumoto,KimitoshiFukunaga,KatsumiNakao.Averageandlocaloxygentransferpropertiesinbubblecolumnwithaxialdistributionofimmobilizedglucoseoxidasegelbeads.ChemicalEngineeringScience2000,55:5405-5414.
